师资队伍

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李燕君

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姓名:李燕君

职称:讲师

职务:

联系电话:18709578217

E-mail:yanjunli@nxu.edu.cn

研究生招生方向:植物生物学

个人简介

科研领域

代表性论文

学习经历、社会兼职及获奖情况

2023-10至今,yL23411永利官网登录讲师

2019-09至2023-06,兰州大学药学院药物化学生物学获理学博士学位

2016-07至2018-12,兰州佛慈制药股份有限公司研究院药物研发工程师

主要研究成果以第一作者在《Industrial Crops and Products》、《Journal of Chromatography A》、《Microchemical Journal》、《Arabian Journal of Chemistry》、《Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy》、《Food and Chemical Toxicology》、《中国中药杂志》和《中草药》等国内外知名期刊上发表研究论文12篇,其中SCI论文9篇。获国家授权发明专利2项。指导本科生获自治区级和校级大学生创新项目各1项。

研究领域

主要从事药用植物的成分分离、分析鉴定、酶抑制剂的筛选、天然产物的活性评价、中药质量评价和功能性产品研发等研究。立足西北特色药用植物资源,结合天然产物化学成分研究与分离分析科学,从事药用植物等复杂体系的分离分析、活性成分筛选等新方法与新技术的建立,以及揭示预防老年性神经退行性疾病和糖尿病等功效物质基础及作用机制方面的研究。

代表性研究成果

1.Yan Jun Li, Fu Qin He, Huan Huan Zhao, Yun Li, Juan Chen*. Screening and identification of acetylcholinesterase inhibitors fromTerminalia chebulafruits by immobilized enzyme on cellulose filter paper coupled with ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and molecular docking [J]. Journal of Chromatography A, 2022, (1663): 462784.

2.Yan Jun Li, Guang Zhen Wan, Fu Chun Xu, Zhao Hui Guo, Juan Chen*. Screening and identification of α-glucosidase inhibitors fromCyclocarya paliurusleaves by ultrafiltration coupled with liquid chromatography-mass spectrometry and molecular docking [J]. Journal of Chromatography A, 2022, (1675): 463160.

3.Yan Jun Li, Yun Li, Juan Chen*. Screening and identification of acetylcholinesterase inhibitors fromTerminalia chebulafruits based on ultrafiltration and ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry [J]. Microchemical Journal, 2021, (168): 106438.

4.Yan Jun Li, Fu-Chun Xu, Guang-Zhen Wan, Juan Chen*. Cellulose filter paper immobilized α-glucosidase as a target enzyme-oriented fishing tool for screening inhibitors fromCyclocarya paliurusleaves [J]. Arabian Journal of Chemistry, 2023, 16(6): 104802.

5.Yan Jun Li, Cai Cai Liang, Ling Jin, Juan Chen*. Inhibition mechanisms of four ellagitannins fromterminalia chebulafruits on acetylcholinesterase by inhibition kinetics, spectroscopy and molecular docking analyses [J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 302: 123115.

6.Yan Jun Li, Yu Dan Wang, Wei Jun Kong, Shi Hai Yang, Jiao Yang Luo, Mei Hua Yang*.Illicium verumessential oil, a potential natural fumigant in preservation of lotus seeds from fungal contamination [J]. Food and Chemical Toxicology, 2020, (141): 111347.

7.Yan Jun Li, Wei Jun Kong, Meng Hua Li, Hong Mei Liu, Xue Zhao, Shi Hai Yang, Mei Hua Yang*.Litsea cubebaessential oil as the potential natural fumigant: Inhibition ofAspergillus flavusand AFB1production in licorice [J]. Industrial Crops and Products, 2016, (80): 186-193.

8.Huan Huan Zhao1,#,Yan Jun Li1,#(共同一作), Zhao Hui Guo, Juan Chen*. Screening of acetylcholinesterase inhibitory and antioxidant active compounds fromTerminalia chebulafruits by spectrum-effect relationship and liquid chromatography‒mass spectrometry analysis [J]. Journal of Separation Science, 2022, 45(18): 3412-3421.

9.李燕君,孔维军,李梦华,杨世海,杨美华*.植物精油抑制真菌及真菌毒素的研究进展[J].中草药, 2016, 47(11): 2011-2018.

10.李燕君,孔维军,胡一晨,赵连华,杨世海,杨美华*.植物源抑真菌剂在中药材养护中的应用前景及展望[J].中国中药杂志, 2015, 40(19): 3729-3736.

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